🔬Beyond AlphaFold: How Boltz is Open-Sourcing the Future of Drug Discovery
Latent Space: The AI Engineer Podcast
- Published
- February 12, 2026
- Duration
- 1h 21m
- Summary source
- description
- Last updated
- Apr 21, 2026
Discusses This podcast features Gabriele Corso and Jeremy Wohlwend, co-founders of Boltz and authors of the Bo…
Summary
This podcast features Gabriele Corso and Jeremy Wohlwend, co-founders of Boltz and authors of the Boltz Manifesto, discussing the rapid evolution of structural biology models from AlphaFold to their own open-source suite, Boltz-1 and Boltz-2. The central thesis is that while single-chain protein structure prediction is largely “solved” through evolutionar…
Show notes
This podcast features Gabriele Corso and Jeremy Wohlwend, co-founders of Boltz and authors of the Boltz Manifesto, discussing the rapid evolution of structural biology models from AlphaFold to their own open-source suite, Boltz-1 and Boltz-2. The central thesis is that while single-chain protein structure prediction is largely “solved” through evolutionary hints, the next frontier lies in modeling complex interactions (protein-ligand, protein-protein) and generative protein design, which Boltz a